CBX family C-terminal motif

Definition

CBX7 and RING1B are components of a Polycomb group (PcG) multiprotein PRC1-like complex which maintains many genes, including Hox genes, transcriptionally repressed during development, signalling and cancer by recognizing trimethylated lysines on histones PMID:21282530. This motif is found at the C terminus of CBX7 where it binds the RAWUL domain of the RING1B protein [[cite:PMID:18588675], [cite:PMID:19791798]].

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• CBX2
• CBX4
• CBX6
• CBX7
• CBX8