Poxin-Schlafen/Schlafen-like, N-terminal domain

Definition

This entry represents a domain found at the N-terminal of Schlafen and Schlafen-like proteins such B3 protein from Orthopoxvirus and poxin-Schlafen from Cowpox virus. It is a nuclease responsible for viral evasion of host cGAS-STING innate immunity PMID:30728498.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• SLFN11
• SLFN12
• SLFN12L
• SLFN13
• SLFN14
• SLFN5