Clathrin adaptor, mu subunit, conserved site

Definition

This entry represents the mu subunit of various clathrin adaptors (AP1, AP2 and AP3) PMID:11583591. The mu subunit regulates the coupling of clathrin lattices with particular membrane proteins by self-phosphorylation via a mechanism that is still unclear PMID:1761056. The mu subunit possesses a highly conserved N-terminal domain of around 230 amino acids, which may be the region of interaction with other AP proteins; a linker region of between 10 and 42 amino acids; and a less well-conserved C-terminal domain of around 190 amino acids, which may be the site of specific interaction with the protein being transported in the vesicle PMID:1761056.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• AP1M1
• AP1M2
• AP2M1
• AP3M1
• AP3M2
• AP4M1