Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II

Definition

Transketolase C-terminal-like domains PMID:8176731 can be found in a number of different enzymes, including the C-terminal domain of the pyruvate dehydrogenase E1 component PMID:11955070, the C-terminal domain of branched-chain alpha-keto acid dehydrogenases PMID:10426958, and domain II of pyruvate-ferredoxin oxidoreductase (PFOR) PMID:11752578. Structural studies reveal this domain to comprise of three layers α/β/α. The mixed β sheet consists of five strands in the order 13245, where strand 1 is antiparallel to the others. This domain has been proposed as a regulatory molecule binding site in transketolase PMID:1628611.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• BCKDHB
• PDHB
• TKT
• TKTL1
• TKTL2