Seroatlas · Protein domains
Complex 1 LYR protein domain
IPR008011
Definition
Proteins containing this domain include an accessory subunit of the higher eukaryotic NADH dehydrogenase complex. In Saccharomyces cerevisiae, the Isd11 protein ([swissprot:Q6Q560]) has been shown to play a role in Fe/S cluster biogenesis in mitochondria [[cite:PMID:16341090], [cite:PMID:16341089]]. This group of proteins was named LYR after a highly conserved tripeptide motif close to the N terminus of these proteins.
8 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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