Keratin-associated protein, PMG type

Definition

This entry represents the keratin-associated proteins, PMG type PMID:10446281. The major structural proteins of mammalian hair are the hair keratin intermediate filaments (KIFs) and the keratin-associated proteins (KRTAPs). In the hair cortex, hair keratins are embedded in an inter-filamentous matrix consisting of KRTAPs which are essential for the formation of a rigid and resistant hair shaft as a result of disulphide bonds between cysteine residues. There are essentially three groups of KRTAPs, viz: the high-sulphur (HS) and ultra-high-sulphur (UHS) KRTAPs (cysteine content: 16-30 and >30 mol%, respectively) and the high-glycine/tyrosine (HGT: 35-60 mol% glycine and tyrosine) KRTAPs.

12 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (12 proteins: gene, accession, name)

• KRTAP11-1
• KRTAP12-2
• KRTAP13-1
• KRTAP13-2
• KRTAP13-3
• KRTAP13-4
• KRTAP15-1
• KRTAP23-1
• KRTAP24-1
• KRTAP25-1
• KRTAP26-1
• KRTAP27-1