ABC1 atypical kinase-like domain

Definition

This entry represents a domain found in Escherichia coli UbiB, known in Providencia stuartii as Aarf, which is required for ubiquinone (CoQ) biosynthesis [[cite:PMID:10960098], [cite:PMID:9422602], [cite:PMID:23709220]]. Some proteins with this domain are described as aarF domain-containing protein kinases (ADCKs). This domain is also found in yeast ABC1 proteins ([swissprot:P27697]) required for function of the mitochondrial bc1 complex PMID:1648478, in which CoQ functions as an essential cofactor.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• ADCK1
• ADCK2
• ADCK5
• COQ8A
• COQ8B