Seroatlas · Human Serome Atlas

MYCNOS

N-cym protein

Also known as: NCYM_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P40205
Gene: MYCNOS
Canonical length: 109 aa

OverviewNCBI Gene

No narrative summary is available for MYCNOS in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

109 residues, UniProt reviewed canonical sequence.

>P40205|MYCNOS
     1  MQHPPCEPGN CLSLKEKKIT EGSGGVCWGG ETDASNPAPA LTACCAAERE ANVEQGLAGR
    61  LLLCNYERRV VRRCKIAGRG RAPLGTRPLD VSSFKLKEEG RPPCLKINK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MYCNOS can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.67

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

Cellular components

KeywordsUniProt

InteractionsUniProt · HPA

Protein binding partners of MYCNOS in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MYCNOS as an antibody target. Whether an autoantibody or antibody against MYCNOS could matter depends on whether native MYCNOS is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MYCNOS is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MYCNOS as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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