Seroatlas · Human Serome Atlas

HOXB-AS3

HOXB-AS3 peptide

Also known as: HAS3P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
C0HLZ6
Gene
HOXB-AS3
Canonical length
53 aa

OverviewNCBI Gene

No narrative summary is available for HOXB-AS3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

53 residues, UniProt reviewed canonical sequence.

>C0HLZ6|HOXB-AS3
     1  MPVLPGTQRY PHQRRRFQAA GGGAESGKRG SEEAPGVAWS GSESGRDAAT PAW

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against HOXB-AS3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.74

OntologyGO

Biological processes

Protein domainsUniProt · Pfam · InterPro

  • HOXB-AS3 peptide
  • HOXB-AS3 peptide

KeywordsUniProt

InteractionsUniProt · HPA

Protein binding partners of HOXB-AS3 in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads HOXB-AS3 as an antibody target. Whether an autoantibody or antibody against HOXB-AS3 could matter depends on whether native HOXB-AS3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

HOXB-AS3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label HOXB-AS3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/HOXB-AS3. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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