Seroatlas · Human Serome Atlas

FKBP9P1

Putative FK506-binding protein 9-like protein

Also known as: FKB9L_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q75LS8
Gene: FKBP9P1
Canonical length: 142 aa

OverviewNCBI Gene

No narrative summary is available for FKBP9P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

142 residues, UniProt reviewed canonical sequence.

>Q75LS8|FKBP9P1
     1  MDMGLREMCV GEKRTVIIPP HLGYGEAGVD GEVPGSAVLV FDIELLELVA GLPEGYMFIW
    61  NGEVSPNLFE EIDKDGNGEV LLEEFSEYIH AQVASGKGKL APGFDAELIV KNMFTNQDRN
   121  GDGKVTAEEF KLKDQEAKQD EL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FKBP9P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.4

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 6% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Molecular functions

Cellular components

endoplasmic reticulum

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FKBP9P1 as an antibody target. Whether an autoantibody or antibody against FKBP9P1 could matter depends on whether native FKBP9P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FKBP9P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FKBP9P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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