Seroatlas · Human Serome Atlas

CENPBD1P

Putative CENPB DNA-binding domain-containing protein 1

Also known as: CENP1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: B2RD01
Gene: CENPBD1P
Canonical length: 187 aa

OverviewNCBI Gene

No narrative summary is available for CENPBD1P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

187 residues, UniProt reviewed canonical sequence.

>B2RD01|CENPBD1P
     1  MPGERPTDAT VIPSAKRERK AITLDLKLEV LRRFEAGEKL SQIAKALDLA ISTVATIRDS
    61  KEKIKASSQI ATPLRASRLT RHRSAVMESM EQLLSLWLED QSQPNATLSA AIVQEKAEFD
   121  DLQREHGEGS QTERFHASQG WLVRFKECHC LPHFKMNSAA PSNKDMYTEM LKSIIEEGEY
   181  TPQVSLT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CENPBD1P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.42

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Molecular functions

DNA binding

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CENPBD1P as an antibody target. Whether an autoantibody or antibody against CENPBD1P could matter depends on whether native CENPBD1P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CENPBD1P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CENPBD1P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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