A6NDN8
Putative ubiquitin-like protein FUBI-like protein ENSP00000310146
Also known as: UBIML_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for A6NDN8 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
102 residues, UniProt reviewed canonical sequence.
>A6NDN8|A6NDN8
1 MRGRRRAWRG AWRGGGAADL SLLCPQVAYV RARELHTLEV TGLETVAQSK AHVASLEGLI
61 PEDKVVLLAG SPLQNEATLG QCGVEALTTL EVVGRRLGVH NVLocalizationUniProt · AlphaFold · HPA
Whether an antibody against A6NDN8 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.45
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads A6NDN8 as an antibody target. Whether an autoantibody or antibody against A6NDN8 could matter depends on whether native A6NDN8 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
A6NDN8 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label A6NDN8 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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