RFX BCD domain

Definition

This domain is found in the site specific DNA binding proteins that are members of the RFX family of transcription factors, including human RFX (1-4/6/8) PMID:18673564. Members of this family are found in animals and fungi, and initially were identified as regulatory factors that bind to a conserved cis-regulatory element called the X-box motif. Members of the RFX family contain a highly conserved HTH DNA-binding domain ([pfam:PF02257]) followed by another conserved domain (BCD) composed of the so-called B,C and D regions which are involved mainly in dimerisation. This entry represents the BCD domain which is predicted to fold into array of alpha-helices.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• RFX1
• RFX2
• RFX3
• RFX4
• RFX6
• RFX8