Growth factor receptor domain IV

Definition

This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain ([pfam:PF00757]) regulates the binding of ligands to the receptor L domains ([pfam:PF01030]) PMID:12154198.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• EGFR
• ERBB2
• ERBB3
• ERBB4
• PCSK5
• PCSK6