Transient receptor ion channel II

Definition

This domain is found in the transient receptor ion channel (Trp) family of proteins. There is strong evidence that Trp proteins are structural elements of calcium-ion entry channels activated by G protein-coupled receptors PMID:10051594. This domain does not tend to appear with the TRP domain ([pfam:PF06011]) but is often found to the C-terminus of Ankyrin repeats ([pfam:PF00023]).

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• TRPC1
• TRPC3
• TRPC4
• TRPC5
• TRPC6
• TRPC7