OB-fold nucleic acid binding domain

Definition

This family contains OB-fold domains that bind to nucleic acids PMID:10829230. The family includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl -tRNA synthetases (See [pfam:PF00152]). Aminoacyl-tRNA synthetases catalyse the addition of an amino acid to the appropriate tRNA molecule [ec:6.1.1.-]. This family also includes part of RecG helicase involved in DNA repair. Replication factor A is a hetero-trimeric complex, that contains a subunit in this family [[cite:PMID:7760808],[cite:PMID:8990123]]. This domain is also found at the C-terminus of bacterial DNA polymerase III alpha chain.

7 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (7 proteins: gene, accession, name)

• DARS1
• DARS2
• KARS1
• NARS1
• NARS2
• RPA1
• STN1