Fibulin, C-terminal Ig-like domain

Definition

This entry represents a C-terminal Ig-like domain found in fibulin proteins mainly from vertebrates. This Ig-like domain seems most closely related to the cadherin domain [interpro:IPR002126]. Fibulins are a family of extracellular matrix glycoproteins characterised by a fibulin-type C-terminal domain preceded by tandem calcium-binding epidermal growth factor (EGF)-like modules. They are involved in protein-protein interaction with the components of basement membrane and extracellular matrix proteins PMID:12778127.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• EFEMP1
• EFEMP2
• FBLN1
• FBLN2
• FBLN5
• FBLN7