Adhesion G-protein coupled receptor
IPR051587
Definition
This family of proteins includes receptors that are known to play a critical role in lung surfactant homeostasis and may also influence adipocyte function. Several members of this family are described as orphan receptors, indicating that their endogenous ligands or functions have not yet been identified. All proteins in this family belong to the G-protein coupled receptor 2 family and are part of the Adhesion G-protein coupled receptor (ADGR) subfamily, which is characterized by a long N-terminus with various adhesion domains that facilitate cell-cell and cell-matrix interactions.
5 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Loading the interactive Seroatlas explorer...