Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

Definition

The entry represents a domain containing a β-α-β(3) motif found in a group of metalloenzymes. The β-α-β(3) motif provides a metal coordination environment for these enzymes, which catalyse different reactions, including isomerisations (glyoxalase I), epimerisations (methylmalonyl-CoA epimerase), oxidative cleavage of C-C bonds (extradiol dioxygenase), and nucleophilic substitutions (fosfomycin resistance proteins) PMID:11076500.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• GLO1
• GLOD4
• GLOD5
• HPD
• HPDL
• MCEE