E3 ubiquitin-protein ligase, SMURF1 type

Definition

This entry represents a set of E3 ubiquitin-protein ligases which accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates, like SMURF1 PMID:11956316, Pub1 PMID:10458166 and RSP5 PMID:9858558. All of them contain a HECT domain PMID:10998601.

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• ITCH
• NEDD4L
• SMURF1
• SMURF2
• WWP1
• WWP2