Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor
IPR016332
Definition
This group represents alpha-1B-glycoproteins and several leukocyte immunoglobulin-like receptors. There are five domains in human alpha 1B-glycoprotein. Mongoose antihemorrhagic factor (AHF1) is a protein, which is homologous to human alpha 1BG, and a supergene family of immunoglobulins PMID:7597727. Alpha-1B-glycoproteins have been found associated with a number of diseases. They have been detected in the urine of children with steroid-resistant minimal change nephrotic syndrome (SRINS) PMID:17959526. It is also found associated with bladder cancer, having been detected in all tumor-bearing patient samples but not samples obtained from non-tumor-bearing individuals PMID:17518487. When the 1694 bp was cloned from human liver Marathon cDNA, which is the alpha-1B glycoprotein precursor gene, it was found that it may be a novel member of immunoglobulin superfamily and could be involved in cell recognition and the regulation of cell behavior PMID:11985261. Polymorphism of Alpha-1-B-glycoprotein (A1BG) has been found in the plasma of several human populations of the Indian subcontinent PMID:7985993.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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