ATP-dependent helicase Rad3/Chl1-like

Definition

This entry includes a group of ATP-dependent helicases, including Rad3/XPD (ERCC2), Chl1/DDX11, DDX12, RTEL1 and BRIP1. Rad3/XPD is a subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3) [[cite:PMID:7961739], [cite:PMID:8631896]]. DDX11/Chl1 is required for sister-chromatid cohesion [[cite:PMID:17611414], [cite:PMID:10931920], [cite:PMID:15226378]].

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• BRIP1
• DDX11
• DDX11L8
• DDX12P
• ERCC2
• RTEL1