Seroatlas · Protein domains
Parallel beta-helix repeat
IPR006626
Definition
The tertiary structures of pectate lyases and rhamnogalacturonase A show a stack of parallel β-strands that are coiled into a large helix. Each coil of the helix represents a structural repeat that, in some homologues, can be recognised from sequence information alone. Conservation of asparagines might be connected with asparagine-ladders that contribute to the stability of the fold. Proteins containing these repeats most often are enzymes with polysaccharide substrates PMID:9724625.
6 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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