Protein disulfide-isomerase, thioredoxin-like domain

Definition

This entry represents a domain found in eukaryotic protein disulphide isomerases (PDI), multifunctional proteins that catalyse the formation, breakage and rearrangement of disulfide bonds [[cite:PMID:25697778], [cite:PMID:32149426], [cite:PMID:21670307], [cite:PMID:27897272]]. PDI generally shows four thioredoxin-like domains. This entry represents the two redox active domains, which are located at the N-and C-terminal ends [[cite:PMID:19119025], [cite:PMID:7983029]].

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• P4HB
• PDIA3
• PDIA4
• PDIA6
• TXNDC5