Glycoside hydrolase family 1

Definition

O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PMID:7624375], [cite:PMID:8535779]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website. Glycoside hydrolase family 1 [cazy:GH1] comprises enzymes with a number of known activities; beta-glucosidase ([ec:3.2.1.21]); beta-galactosidase ([ec:3.2.1.23]); 6-phospho-beta-galactosidase ([ec:3.2.1.85]); 6-phospho-beta-glucosidase ([ec:3.2.1.86]); lactase-phlorizin hydrolase ([ec:3.2.1.62]), ([ec:3.2.1.108]); beta-mannosidase ([ec:3.2.1.25]); myrosinase ([ec:3.2.1.147]).

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• GBA3
• KL
• KLB
• LCT
• LCTL