Seroatlas · Human Serome Atlas

ZSCAN5DP

Putative zinc finger and SCAN domain-containing protein 5D

Also known as: ZSA5D_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0CG00
Gene: ZSCAN5DP
Canonical length: 497 aa

OverviewNCBI Gene

No narrative summary is available for ZSCAN5DP in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

497 residues, UniProt reviewed canonical sequence.

>P0CG00|ZSCAN5DP
     1  MGQCRNWKWG LESFDFSINR RSSAPGQLES ASQMRESWRH KAGRRMFSCP EESDPIQALR
    61  KLTELCHLWL RPDLHTKEQI LDMLVMEQFM ISMPQELQVL VKVNGVQSCK DLEDLLRNNR
   121  RPKKWSVVNF LGKEYLMQES DVEMAEIPAS VRDDPRGVSS QRASSVNEMR PGEGQASQEL
   181  QTLPRVPALS RRQEEDFLLP ETTVMKSAPK ALRPKPTLEK DLNVDREENT GLTSPEPQLP
   241  NGPSVVGAKE GKEPKKRASV ENVDADTPSA CVVEREASTH SGSRGDALNL RCPKRSKPDA
   301  TSISQEGPQG GATPVGNSES PGKPEINSVY SPGPAGAVSH PNGQEAKELL PFACGVCNKR
   361  FTCNSKLAIH MRSHTGERPF QCNFCERCFT QLSDLRVHQR IHTGEKPYTC DICHKRFNRM
   421  FSLKCHKRSH TGEKPYKCKD CNQVFTYRKN LNEHKLIHSG EKPYKCPKCL RAFRRPETLK
   481  YHQKTHQETT APRECEG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZSCAN5DP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.55

OntologyGO

Biological processes

regulation of transcription by RNA polymerase II

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZSCAN5DP as an antibody target. Whether an autoantibody or antibody against ZSCAN5DP could matter depends on whether native ZSCAN5DP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZSCAN5DP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZSCAN5DP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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