Seroatlas · Human Serome Atlas

ZNF876P

Putative zinc finger protein 876

Also known as: Z876P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q49A33
Gene: ZNF876P
Canonical length: 203 aa

OverviewNCBI Gene

No narrative summary is available for ZNF876P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

203 residues, UniProt reviewed canonical sequence.

>Q49A33|ZNF876P
     1  MHTGEKPYTC EECVKLLTNP QALLYTGAFI LNKNFTNVKN AAKPLLNPHP LINKRIHTGE
    61  KPYTCEECGK AFYRSSHLTE HKNIHTGEKS YKCEECGNAF YRSSHLTKHK RIHSGQKPYK
   121  CEECGKAFRQ SSALNEHKKI HTAEKPYKCK ECGKAFRWSR SLNEHTNIHI GEKPYTCEEC
   181  GKDFTWSSTL TVHQRIQTGE KHS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ZNF876P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.46

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

regulation of DNA-templated transcription

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ZNF876P as an antibody target. Whether an autoantibody or antibody against ZNF876P could matter depends on whether native ZNF876P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ZNF876P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ZNF876P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...