Seroatlas · Human Serome Atlas

TTC41P

Putative tetratricopeptide repeat protein 41

Also known as: TTC41_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q6P2S7
Gene
TTC41P
Canonical length
1318 aa

OverviewNCBI Gene

No narrative summary is available for TTC41P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

1318 residues, UniProt reviewed canonical sequence.

>Q6P2S7|TTC41P
     1  MSQKTNENVE RYTQFLQKPQ KPIQPYICST LNDFQEERDF LANNIFPQLN ELCNSWGTYF
    61  KAVDLSWSAL KAPKSLPTHL FRQYSCLRSQ RLKLCLDYVN SCFPFFICML GQTYGDFLPD
   121  YSHFMTSKVT RLSSLSKVEN LYVAAKNGYP WVLENPSCSL TEFEIIQAAF LNESQFQYFY
   181  FRTGTTLLKA LDDEKKGERL PSSSSTNEEE TLRIGKLKAK IISKGLPVRF YSDLHELGEL
   241  VFKDWSVVIE KLHPATLMIE NIDYKHSFER FYHEEFTEKC KQMCVISKES DRTFEILEKF
   301  ALKDVELDFN NVAADSSLDS VPRFFRINPT PTYKSILLLS REHGCGKSTL IANWVNYFKK
   361  KHPSMLLIPH FVGSTCESSY IMSVIHYFIT ELQYRNYGTQ LETDILNEDS DGLVFSFLVE
   421  VFIASISLKP CILVLDGIEE LIGIYGISGQ KVKDFSWLPH SLSPHCKFIM STVSSSLSYK
   481  SLCARPDVRT VELISTGDEE TKLNIFRKHL SIPMMDPFEQ STQALRKKPD LSPLKLTILA
   541  NELKEYRINH NEFQCMKEYL EAVSVQELWE LVLKRWIEDY SWTFQPKRAN SDTVASGEGL
   601  DSWVADALCL LCLSHGGLAE DELLQLLDML GYRNHYKVTA LHWAAFRNAT KQWVQEKPNG
   661  LLYFWHQSLS AVEHKLLGVI TPVESSPCSF QTPMNHKKTH FHQVLIRYFQ RQTSFWRVYQ
   721  ELPWHMKMSG CLRGLCGFLS SPTITDFISK IQSLGFWTRL HLIHFWNVLL EAGYDVSEAY
   781  LLSVAKIKAD QCHTMRKSGT LSVLQCRLIE LTVLDKCRLM FFIGSFLKFM GKTNEAEELF
   841  LSVEDMLVQS QSMTDMLLKV QNAIGELYLE TGMTQEGFQY FQKAWSSMLR LSLSDLEDSR
   901  DLVKQKVRVL DNLAKSASEE YLKENHILEY ATEISNLLDN NPRDQATMKY IEGVLMFVAG
   961  NTSLAKMKLR ECLNIRKSLF GKKNMLVGEV MEFLADLLFF PQRDSKKSQR KQVLKYYKQV
  1021  IKIKENAETL AKSSLLRKQL SISLSDTLCK LAGHLLASDS CHHVMIEAVG YLYRSVDLRV
  1081  IHLGSSHSSI HGIHGILHLL REIEWIRSRR YWPQGMSQQH SEGSRNGFSL WEHLVKLNYH
  1141  SAQSSNTVSS AMCMNADKLH RARRMDLAPQ TISDKSKCAP GKGKKKPIIC ISAEEKIQRK
  1201  TQNNAEIWNG SGKEASKKKT DYSSNILSLG KMNGLIKLSR QRILLAKSES GEGEITTIYH
  1261  HPLPWPVSTK NPGESEFISE KWLFHSPDYI SISQKSFLQR RLHIETKLLK TSNDINKE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against TTC41P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Intracellular
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.31

OntologyGO

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads TTC41P as an antibody target. Whether an autoantibody or antibody against TTC41P could matter depends on whether native TTC41P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

TTC41P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label TTC41P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/TTC41P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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