Seroatlas · Human Serome Atlas

SLC22A20P

Solute carrier family 22 member 20

Also known as: S22AK_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NK97
Gene: SLC22A20P
Canonical length: 555 aa

OverviewNCBI Gene

No narrative summary is available for SLC22A20P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

555 residues, UniProt reviewed canonical sequence.

>A6NK97|SLC22A20P
     1  MAFTDLLDAL GSMGRFQLNH TALLLLPCGL LACHNFLQNF TAAVPPHHCR GPANHTEAST
    61  NDSGAWLRAT IPLDQLGAPE PCRRFTKPQW ALLSPNSSIP GAATEGCKDG WVYNRSVFPS
   121  TIVMEWDLVC EARTLRDLAQ SVYMAGVLVG AAVFGSLADR LGCKGPLVWS YLQLAASGAA
   181  TAYFSSFSAY CVFRFLMGMT FSGIILNSVS LVVEWMPTRG RTVAGILLGY SFTLGQLILA
   241  GVAYLIRPWR CLQFAISAPF LIFFLYSWWL PESSRWLLLH GKSQLAVQNL QKVAAMNGRK
   301  EEGERLTKEV MSSYIQSEFA SVCTSNSILD LFRTPAIRKV TCCLMVIWFS NSVAYYGLAM
   361  DLQKFGLSLY LVQALFGIIN TPAMLVATAT MIYVGRRATV ASFLILAGLM VIANMFVPEG
   421  TQILCTAQAA LGKGCLASSF ICVYLFTGEL YPTEIRQMGM GFASVHARLG GLTAPLVTTL
   481  GEYSTILPPV SFGATAILAG LAVCVLTETR NMPLVETIAA MERRVKEGSS KKHVEEKSEE
   541  ISLQQLRASP LKETI

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SLC22A20P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 11
Mean surface accessibility (rSASA): 0.26

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

Molecular functions

transmembrane transporter activity

Cellular components

membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SLC22A20P as an antibody target. Whether an autoantibody or antibody against SLC22A20P could matter depends on whether native SLC22A20P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SLC22A20P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SLC22A20P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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