Seroatlas · Human Serome Atlas

SEPTIN14P20

Putative RNA-binding regulatory peptide

Also known as: RBRP_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: C0HM01
Gene: SEPTIN14P20
Canonical length: 71 aa

OverviewNCBI Gene

No narrative summary is available for SEPTIN14P20 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

71 residues, UniProt reviewed canonical sequence.

>C0HM01|SEPTIN14P20
     1  MIQQEEIRKL EEEKKQLEGE IIDFYKMKAA SEALQTQLST DTKKDKHPDP YEFLLLRKIK
    61  HPGFNEELSP C

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against SEPTIN14P20 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.55

OntologyGO

Biological processes

mRNA stabilization
positive regulation of mRNA binding

InteractionsUniProt · HPA

Protein binding partners of SEPTIN14P20 in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

IGF2BP1

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads SEPTIN14P20 as an antibody target. Whether an autoantibody or antibody against SEPTIN14P20 could matter depends on whether native SEPTIN14P20 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

SEPTIN14P20 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label SEPTIN14P20 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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