Seroatlas · Human Serome Atlas

NSUN5P1

Putative NOL1/NOP2/Sun domain family member 5B

Also known as: NSN5B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q3KNT7
Gene: NSUN5P1
Canonical length: 163 aa

OverviewNCBI Gene

No narrative summary is available for NSUN5P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

163 residues, UniProt reviewed canonical sequence.

>Q3KNT7|NSUN5P1
     1  MATLLAWVGV SCCELAEEDF LAVSPLDPRY REVHYVLLDP SCSGSGMPSR QLEDPGAGTP
    61  SPVRLHALAG FQQRALCHAL TFPSLQRLVY SMCSLCQEEN EDMVPDALQQ NPGAFRLAPA
   121  LPARPHRGLS TFPGAEHCLR ASPKTTLSGG FFVAVIERVE MPT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against NSUN5P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.34

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 6% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

RNA methylation

Molecular functions

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads NSUN5P1 as an antibody target. Whether an autoantibody or antibody against NSUN5P1 could matter depends on whether native NSUN5P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

NSUN5P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label NSUN5P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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