Seroatlas · Human Serome Atlas

NBPF7P

Putative NBPF family member NBPF7

Also known as: NBPF7_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C2Y1
Gene: NBPF7P
Canonical length: 421 aa

OverviewNCBI Gene

No narrative summary is available for NBPF7P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

421 residues, UniProt reviewed canonical sequence.

>P0C2Y1|NBPF7P
     1  MCLRFFSPVP GSTSSATNVT MVVSAGPWSS EKAEMNILEI NEKLRPQLAE NKQQFRNMKQ
    61  KFLVTQMAGF LANQQNKYKY EECKDLIKSM LREELQFKEE KLAEQLKQAE ELRQYKVLVH
   121  SQERELIQLR EKLREGRDAS HSLNQHLQAL LTPDKHDNSQ GQDFREQLAE GCRLARHLVH
   181  KLSPENDTDE DENDKTKELD KVQESPAPRE EQKAEEKEVP EDSLEECAIT YSNSHGPSDS
   241  NPPHKNIKIT SEEDKVNSIL VVDSESSQDE WQDALNILLE NQNDDEEEEG KAPVPPQVTL
   301  WICGLKLQES EEKEVLQDSP EERVTTSCSD HDVSQSYQPC EGTFLALVEQ KVCSAQDVAS
   361  EHSNSKGEET PLGFPDTKYC WKDEKDERMS QKVAFLLDEK NYNSKPSSIP NTTLQGSFTE
   421  D

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against NBPF7P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.63

OntologyGO

Cellular components

cytoplasm

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads NBPF7P as an antibody target. Whether an autoantibody or antibody against NBPF7P could matter depends on whether native NBPF7P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

NBPF7P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label NBPF7P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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