Seroatlas · Human Serome Atlas

NBPF5P

Putative NBPF family member NBPF5

Also known as: NBPF5_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q86XG9
Gene: NBPF5P
Canonical length: 351 aa

OverviewNCBI Gene

No narrative summary is available for NBPF5P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

351 residues, UniProt reviewed canonical sequence.

>Q86XG9|NBPF5P
     1  MVVSADPLSS ERAEMNILEI NQELRSQLAE SNQQFRDLKE KFLITQATAY SLANQLKKYK
    61  CEEYKDIIDS VLRDELQSME KLAEKLRQAE ELRQYKALVH SQAKELTQLR EKLREGRDAS
   121  RWLNKHLKTL LTPDDPDKSQ GQDLREQLAE GHRLAEHLVH KLSPENDEDE DEDEDDKDEE
   181  VEKVQESPAP REVQKTEEKE VPQDSLEECA VTCSNSHNPS NSNQPHRSTK ITFKEHEVDS
   241  ALVVESEHPH DEEEEALNIP PENQNDHEEE EGKAPVPPRH HDKSNSYRHR EVSFLALDEQ
   301  KVCSAQDVAR DYSNPKWDET SLGFLDTPLA RRESVALKGR TRSWQHSSHA N

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against NBPF5P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.62

OntologyGO

Cellular components

cytoplasm

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads NBPF5P as an antibody target. Whether an autoantibody or antibody against NBPF5P could matter depends on whether native NBPF5P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

NBPF5P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label NBPF5P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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