Seroatlas · Human Serome Atlas

MEIS3P2

Putative homeobox protein Meis3-like 2

Also known as: ME3L2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8K0S8
Gene: MEIS3P2
Canonical length: 358 aa

OverviewNCBI Gene

No narrative summary is available for MEIS3P2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

358 residues, UniProt reviewed canonical sequence.

>A8K0S8|MEIS3P2
     1  MARRYDELPH YPSIADGPAA LAGFPEAVPA APGPYGPHRP PQPLPPGLDS DGLKRDKDEI
    61  YGHPLFPLLA LVFEKCELAT CSPRDGAGAG LGTPRGGDVC SSDSFNEDNT AFAKQVRSER
   121  PFFSSNPELD NLMIQAIQVL RFHLLELEKG KMPIDLVIED RDGGCREDFE DYPASCLSLP
   181  DQNNIWIRDH EDSGSVHLGT PGPSSGGLAS QSGDNSSDQG VGLDTSVASP SSGGEDEDLD
   241  QEPRRNKKRG IFPKVATNIM RAWLFQHLWH PYPSEEQKKQ LVQDTGLTIL QVNNWFINAR
   301  RRMVQPMIDQ SNRIGQGAAF SPEGQPIGGY TETEPHVAFR PPASVGMSLN LEGEWHYL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MEIS3P2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.59

OntologyGO

Biological processes

Molecular functions

Cellular components

nucleus

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MEIS3P2 as an antibody target. Whether an autoantibody or antibody against MEIS3P2 could matter depends on whether native MEIS3P2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MEIS3P2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MEIS3P2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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