Seroatlas · Human Serome Atlas

MARCHF6-DT

Poly-ADP-ribosylation-amplifying and CtIP-maintaining micropeptide

Also known as: PACMP_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
P0DW81
Gene
MARCHF6-DT
Canonical length
44 aa

OverviewNCBI Gene

No narrative summary is available for MARCHF6-DT in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

44 residues, UniProt reviewed canonical sequence.

>P0DW81|MARCHF6-DT
     1  MAASGGTKKA QSGGRRLREP SSRPSRRARQ RPRRGALRKA GRFL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against MARCHF6-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Intracellular
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.75

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

  • PAR-amplifying and CtIP-maintaining micropeptide
  • PAR-amplifying and CtIP-maintaining micropeptide

KeywordsUniProt

InteractionsUniProt · HPA

Protein binding partners of MARCHF6-DT in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads MARCHF6-DT as an antibody target. Whether an autoantibody or antibody against MARCHF6-DT could matter depends on whether native MARCHF6-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

MARCHF6-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label MARCHF6-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/MARCHF6-DT. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

© 2026 · Seroatlas, Discover Oregon LLC · Terms of use

Loading the interactive Seroatlas protein explorer...