Seroatlas · Human Serome Atlas

KRT87P

Putative keratin-87 protein

Also known as: KR87P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A6NCN2
Gene
KRT87P
Canonical length
255 aa

OverviewNCBI Gene

No narrative summary is available for KRT87P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

255 residues, UniProt reviewed canonical sequence.

>A6NCN2|KRT87P
     1  MEANSGRLAS ELNHVQEVLE GYKKKYEEEV ALRATAENEF VALKKDVDCA YLRKSDLEAN
    61  VEALTQEIDF LRRLYEEEIR VLQSHISDTS VVVKMDNSRD LNMHCVITEI KAQYDDIATR
   121  SRAEAESWYR SKCEEMKATV IRHGETLRRT KEEINELNRM IQRLTAEVEN AKCQNSKLEA
   181  AVAQSEQQGE AALSDARCKL AELEGALQKA KQDMACLIRE YQEVMNSKLA WTLRSPPTGA
   241  CWRARSRGCV RALVL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against KRT87P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Secreted
Secreted
Yes
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.5

OntologyGO

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads KRT87P as an antibody target. Whether an autoantibody or antibody against KRT87P could matter depends on whether native KRT87P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

KRT87P is annotated as secreted, so native KRT87P circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label KRT87P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/KRT87P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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