Seroatlas · Human Serome Atlas

HSP90B2P

Putative endoplasmin-like protein

Also known as: ENPLL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q58FF3
Gene: HSP90B2P
Canonical length: 399 aa

OverviewNCBI Gene

No narrative summary is available for HSP90B2P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

399 residues, UniProt reviewed canonical sequence.

>Q58FF3|HSP90B2P
     1  MAETIQEVED EYKAFCKSFS KESDDPVACI HFTAEGEVTF KSILFVPTFV PRGLFDEYGS
    61  KKSDYIKLYV RCVFITDDFR DTMPKNLNFV KGVVDSGGLS LNVSCETLQQ HKLLKVIRKK
   121  LVHKTLDMIK KIADEKYNDT FWKEFGTNIK LGVIEDHSNR TCLAKLLRFQ SSHHPADITS
   181  LHQDVERMKE KQDKICLMAG GYEVIYLTEP VVEYCIQALP EFDGKRFQNV AKEGVKFDDS
   241  EKTKESHEAV EKEFEPLPNW VKDKAIKDKI EKAMVSQCLT ESLCALVASQ YGWSGNMERI
   301  MKAQAYQTGK GISTNYHASR KKTFEINPRH PLIRDMLRRI KEDEDDKTVL DLAVVEEPDE
   361  EPEETAEDKE QDKDKEMDVG TDEEKQETAK ESTAEKDEL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against HSP90B2P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Other membrane
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.34

OntologyGO

Biological processes

protein folding

Molecular functions

Cellular components

mitochondrial inner membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads HSP90B2P as an antibody target. Whether an autoantibody or antibody against HSP90B2P could matter depends on whether native HSP90B2P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

HSP90B2P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label HSP90B2P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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