Seroatlas · Human Serome Atlas

H2BC19P

Putative histone H2B type 2-D

Also known as: H2B2D_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6DRA6
Gene: H2BC19P
Canonical length: 164 aa

OverviewNCBI Gene

No narrative summary is available for H2BC19P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

164 residues, UniProt reviewed canonical sequence.

>Q6DRA6|H2BC19P
     1  MPEPAKFAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSI YVYKVLKRVH PDTGIWCKAM
    61  GIMNSFLNDI FERIAGEASR LAHYNKRSTI TSRRSRRPCA CCCPASWPST PCPRAPRRSP
   121  STPAPSESLP GPGARSLPPS LPPRVAGCFV SKGSFQGHLT PLVK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against H2BC19P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.63

OntologyGO

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads H2BC19P as an antibody target. Whether an autoantibody or antibody against H2BC19P could matter depends on whether native H2BC19P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

H2BC19P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label H2BC19P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...