Seroatlas · Human Serome Atlas

FXYD6P3

Putative FXYD domain-containing ion transport regulator 8

Also known as: FXYD8_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P58550
Gene: FXYD6P3
Canonical length: 94 aa

OverviewNCBI Gene

No narrative summary is available for FXYD6P3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

94 residues, UniProt reviewed canonical sequence.

>P58550|FXYD6P3
     1  MEVVLIFVYS LLVPVVLASA AKEKEIDPFH YNYQTLRIGG LVFDVVLFLV PSCHLLSHRC
    61  KCSFNQKPQD PGDKEAQVEN FITANAKEPQ KAKN

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FXYD6P3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.56

OntologyGO

Biological processes

Molecular functions

sodium channel regulator activity

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FXYD6P3 as an antibody target. Whether an autoantibody or antibody against FXYD6P3 could matter depends on whether native FXYD6P3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FXYD6P3 is annotated at the cell surface, where native FXYD6P3 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label FXYD6P3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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