Seroatlas · Human Serome Atlas

FAM86C1P

Putative protein FAM86C1P

Also known as: F86C1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9NVL1
Gene: FAM86C1P
Canonical length: 165 aa

OverviewNCBI Gene

No narrative summary is available for FAM86C1P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

165 residues, UniProt reviewed canonical sequence.

>Q9NVL1|FAM86C1P
     1  MAPEENAGSE LLLQSFKRRF LAARALRSFR WQSLEAKLRD SSDSELLRDI LQKHEAVHTE
    61  PLDELYEVLV ETLMAKESTQ GHRSYLLTCC IAQKPSCRWS GSCGGWLPAG STSGLLNSTW
   121  PLPSATQRCA SCSPPSYAGL GSDGKRKLIM TRNCFPTEST WRWQS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FAM86C1P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.57

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 8% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

InteractionsUniProt · HPA

Protein binding partners of FAM86C1P in the human serome: UniProt-annotated complex subunits plus reported interactors. Each links to its own Seroatlas record.

EEF2KMT

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FAM86C1P as an antibody target. Whether an autoantibody or antibody against FAM86C1P could matter depends on whether native FAM86C1P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FAM86C1P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FAM86C1P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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