Seroatlas · Human Serome Atlas

FABP5P3

Putative fatty acid-binding protein 5-like protein 3

Also known as: FB5L3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MUU1
Gene: FABP5P3
Canonical length: 101 aa

OverviewNCBI Gene

No narrative summary is available for FABP5P3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

101 residues, UniProt reviewed canonical sequence.

>A8MUU1|FABP5P3
     1  MGAMAKPDCI ITCDSKNLTI KTESTLKTTQ FSGTLGEKFE ENTADGRRTQ TVCNFTDGAL
    61  VQHQEWDGKE STITRKLKDG KLVVERVMNH VACTRIYEKA Q

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FABP5P3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.38

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

fatty acid transport

Molecular functions

fatty acid binding

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FABP5P3 as an antibody target. Whether an autoantibody or antibody against FABP5P3 could matter depends on whether native FABP5P3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FABP5P3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FABP5P3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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