Seroatlas · Human Serome Atlas

BARGIN

Bargin

Also known as: BGIN_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZT62
Gene: BARGIN
Canonical length: 677 aa

OverviewNCBI Gene

No narrative summary is available for BARGIN in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

677 residues, UniProt reviewed canonical sequence.

>Q6ZT62|BARGIN
     1  MDRGLPGPAT PAVTPQPPAR PQDDEEAAAP HAAAGPDGQL GTVEQRLEPA KRAAHNIHKR
    61  LQACLQGQSG ADMDKRVKKL PLMALSTTMA ESFKELDPDS SMGKALEMSC AIQNQLARIL
   121  AEFEMTLERD VLQPLSRLSE EELPAILKHK KSLQKLVSDW NTLKSRLSQA TKNSGSSQGL
   181  GGSPGSHSHT TMANKVETLK EEEEELKRKV EQCRDEYLAD LYHFVTKEDS YANYFIRLLE
   241  IQADYHRRSL SSLDTALAEL RENHGQADHS PSMTATHFPR VYGVSLATHL QELGREIALP
   301  IEACVMMLLS EGMKEEGLFR LAAGASVLKR LKQTMASDPH SLEEFCSDPH AVAGALKSYL
   361  RELPEPLMTF DLYDDWMRAA SLKEPGARLQ ALQEVCSRLP PENLSNLRYL MKFLARLAEE
   421  QEVNKMTPSN IAIVLGPNLL WPPEKEGDQA QLDAASVSSI QVVGVVEALI QSADTLFPGD
   481  INFNVSGLFS AVTLQDTVSD RLASEELPST AVPTPATTPA PAPAPAPAPA PALASAATKE
   541  RTESEVPPRP ASPKVTRSPP ETAAPVEDMA RRSTGSLAAA VETASGRQAL VVGKPSPYMF
   601  ECITENFSID PARTLMVGDR LETDILFGHR CGMTTVLTLT GVSRLEEAQA YLAAGQHDLV
   661  PHYYVESIAD LTEGLED

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against BARGIN can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.39

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads BARGIN as an antibody target. Whether an autoantibody or antibody against BARGIN could matter depends on whether native BARGIN is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

BARGIN is annotated at the cell surface, where native BARGIN is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label BARGIN as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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