BAGE4
B melanoma antigen 4
Also known as: BAGE4_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for BAGE4 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
39 residues, UniProt reviewed canonical sequence.
>Q86Y28|BAGE4
1 MAAGAVFLAL SAQLLQARLM KEESPVVSWW LEPEDGTALLocalizationUniProt · AlphaFold · HPA
Whether an antibody against BAGE4 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Secreted
- Secreted
- Yes
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.61
OntologyGO
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads BAGE4 as an antibody target. Whether an autoantibody or antibody against BAGE4 could matter depends on whether native BAGE4 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
BAGE4 is annotated as secreted, so native BAGE4 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.
Annotation status
The present source text does not explicitly label BAGE4 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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