Seroatlas · Human Serome Atlas

BAGE3

B melanoma antigen 3

Also known as: BAGE3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q86Y29
Gene: BAGE3
Canonical length: 109 aa

OverviewNCBI Gene

No narrative summary is available for BAGE3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

109 residues, UniProt reviewed canonical sequence.

>Q86Y29|BAGE3
     1  MAAGVVFLAL SAQLLQARLM KEESPVVSWR LEPEDGTALD VHFVSTLEPL SNAVKRNVPR
    61  CIIILVLQEP TPFRISVTSS CFVQNTLTKL LKDRRKMQTV QCATAQETS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against BAGE3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.44

OntologyGO

Cellular components

extracellular region

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads BAGE3 as an antibody target. Whether an autoantibody or antibody against BAGE3 could matter depends on whether native BAGE3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

BAGE3 is annotated as secreted, so native BAGE3 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label BAGE3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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