Seroatlas · Human Serome Atlas

BAGE

B melanoma antigen 1

Also known as: BAGE1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q13072
Gene: BAGE
Canonical length: 43 aa

OverviewNCBI Gene

No narrative summary is available for BAGE in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

43 residues, UniProt reviewed canonical sequence.

>Q13072|BAGE
     1  MAARAVFLAL SAQLLQARLM KEESPVVSWR LEPEDGTALC FIF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against BAGE can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.6

OntologyGO

Cellular components

extracellular region

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads BAGE as an antibody target. Whether an autoantibody or antibody against BAGE could matter depends on whether native BAGE is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

BAGE is annotated as secreted, so native BAGE circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label BAGE as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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