Neurobeachin/BDCP, DUF4704 alpha solenoid region

Definition

This domain of unknown function is found in eukaryotes on neurobeachin and BEACH domain-containing proteins (BDCPs) [[cite:PMID:17215302],[cite:PMID:32154999]]. Mutations in this proteins are associated with Lipopolysaccharide-responsive and beige-like anchor (LRBA) deficiency PMID:32154999. According to structure prediction is adopts an alpha-helical solenoid structure.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• LRBA
• NBEA
• NBEAL1
• NBEAL2
• NBEAP1