RyR and IP3R Homology associated

Definition

This eukaryotic domain is found in ryanodine receptors (RyR) and inositol 1,4,5-trisphosphate receptors (IP3R) which together form a superfamily of homotetrameric ligand-gated intracellular Ca2+ channels PMID:14516409. There seems to be no known function for this domain PMID:10664581. Also see the IP3-binding domain [pfam:PF01365] and [pfam:PF02815].

6 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (6 proteins: gene, accession, name)

• ITPR1
• ITPR2
• ITPR3
• RYR1
• RYR2
• RYR3