Seroatlas · Protein domains
Dynein heavy chain, N-terminal region 1
PF08385
Definition
Dynein heavy chains interact with other heavy chains to form dimers, and with intermediate chain-light chain complexes to form a basal cargo binding unit PMID:10862709. The region featured in this family includes the sequences implicated in mediating these interactions PMID:10336435. It is thought to be flexible and not to adopt a rigid conformation PMID:10862709.
9 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
Loading the interactive Seroatlas explorer...