PHR domain

Definition

This domain is called PHR as it was original found in the proteins PAM ([swissprot:O75592]), highwire ([swissprot:Q9NB71]) and RPM ([swissprot:Q17551]) PMID:12878161. This domain can be duplicated in the highwire, PFAM and PRM sequence. The C-terminal region of the protein BTBD1 includes the PHR domain and is known to interact with Topoisomerase I, an enzyme which relaxes DNA supercoils PMID:11818025.

5 human proteins with this domain

Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.

Download CSV (5 proteins: gene, accession, name)

• BTBD1
• BTBD2
• BTBD3
• BTBD6
• MYCBP2