Neural and epithelial cell adhesion domain-containing protein
IPR051170
Definition
This family of proteins includes cell adhesion molecules that are primarily involved in neural development and function. They play crucial roles in neuron-neuron adhesion, neurite outgrowth, fasciculation, and the development of nerve fascicles. Some members are implicated in maintaining the integrity of the trans-epithelial diffusion barrier and may also participate in early neuronal differentiation. Additionally, certain proteins within this family have been identified as receptors for various microbial infections, indicating a role in immune response or pathogen interaction. The family also includes proteins that contribute to cell migration, proliferation, morphology, and survival, particularly in the context of renal epithelial cells. Overall, these proteins are essential for proper neural network formation and maintenance, as well as other cellular processes.
11 human proteins with this domain
Each is a reviewed human protein in the Seroatlas serome and a potential autoantibody target; this domain groups them into one antibody-relevant category. Every entry links to its own record.
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